{"id":10096,"date":"2022-10-24T15:32:23","date_gmt":"2022-10-24T15:32:23","guid":{"rendered":"https:\/\/www.danubia.com\/?post_type=project&p=10096"},"modified":"2022-11-29T17:16:22","modified_gmt":"2022-11-29T17:16:22","slug":"kapillaris-elektroforezis-tomegspektrometer-csatolas","status":"publish","type":"project","link":"https:\/\/www.danubia.com\/hu\/ipmall\/kapillaris-elektroforezis-tomegspektrometer-csatolas\/","title":{"rendered":"Kapill\u00e1ris elektrofor\u00e9zis – t\u00f6megspektrom\u00e9ter csatol\u00e1s"},"content":{"rendered":"

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Kapill\u00e1ris elektrofor\u00e9zis – t\u00f6megspektrom\u00e9ter csatol\u00e1s<\/p>\n

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Reprezentat\u00edv \u00fcgysz\u00e1m: P1500200<\/a>
Oltalom: Szabadalom
Ipar\u00e1g: Gy\u00f3gyszeripar \u00e9s kozmetikai ipar, Eg\u00e9szs\u00e9g\u00fcgy, orvosi eszk\u00f6z\u00f6k \u00e9s egy\u00e9b m\u0171szerek
Hasznos\u00edt\u00e1si enged\u00e9ly vagy tulajdonjog \u00e1truh\u00e1z\u00e1s megjel\u00f6l\u00e9se: licencia<\/p>\n

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R\u00f6vid le\u00edr\u00e1s<\/strong><\/span>
A tal\u00e1lm\u00e1ny egy ultra-kompakt kapill\u00e1ris elektrofor\u00e9zis (CE) k\u00e9sz\u00fcl\u00e9k, amely \u00f6n\u00e1ll\u00f3an \u00e9s tetsz\u0151leges t\u00f6megspektrom\u00e9terrel (MS) \u00f6sszekapcsolva egyar\u00e1nt k\u00e9pes m\u0171k\u00f6dni, egy, a CE k\u00e9sz\u00fcl\u00e9kre szerelhet\u0151 gy\u00e1rtm\u00e1nyspecifikus adapter seg\u00edts\u00e9g\u00e9vel. Jelen bioanalitikai eszk\u00f6z alkalmas k\u00fcl\u00f6nb\u00f6z\u0151 mint\u00e1k CE-ESI-MS alap\u00fa anal\u00edzis\u00e9re, kialak\u00edt\u00e1s\u00e1t tekintve kompakt m\u00e9ret\u0171, k\u00f6nnyen haszn\u00e1lhat\u00f3 \u00e9s robusztus k\u00e9sz\u00fcl\u00e9k, ami a t\u00f6megspektrom\u00e9ter ESI ionforr\u00e1s\u00e1ba integr\u00e1lja a kapill\u00e1ris elektrofor\u00e9zis elv\u00e1laszt\u00e1st r\u00f6vid elv\u00e1laszt\u00e1si kapill\u00e1ris alkalmaz\u00e1s\u00e1val, illetve kompatibilis a piacon jelenleg el\u00e9rhet\u0151 k\u00fcl\u00f6nb\u00f6z\u00f6 fajta 15 t\u00f6megspektrom\u00e9terekkeL Az UCESI k\u00e9sz\u00fcl\u00e9k (100) egy gy\u00e1rtm\u00e1nyspecifikus r\u00f6gz\u00edt\u0151keretb\u0151l (101), egy termoszt\u00e1lhat\u00f3 kapill\u00e1ris modulb\u00f3l (102), egy ESI portaszt\u00f3b\u00f3l (103), egy mozgathat\u00f3 mintatart\u00f3 t\u00e1lc\u00e1b\u00f3l (104) \u00e9s egy kiszolg\u00e1l\u00f3 egys\u00e9gb\u0151l (105) \u00e1ll.<\/p>\n

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A tal\u00e1lm\u00e1ny egy ultra-kompakt kapill\u00e1ris elektrofor\u00e9zis (CE) k\u00e9sz\u00fcl\u00e9k, amely \u00f6n\u00e1ll\u00f3an \u00e9s tetsz\u0151leges t\u00f6megspektrom\u00e9terrel (MS) \u00f6sszekapcsolva egyar\u00e1nt k\u00e9pes m\u0171k\u00f6dni, egy, a CE k\u00e9sz\u00fcl\u00e9kre szerelhet\u0151 gy\u00e1rtm\u00e1nyspecifikus adapter seg\u00edts\u00e9g\u00e9vel.<\/p>\n","protected":false},"author":1,"featured_media":10098,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"

[et_pb_section fb_built=\"1\" specialty=\"on\" _builder_version=\"3.22\" inner_max_width=\"none\"][et_pb_column type=\"1_4\" _builder_version=\"3.25\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_image src=\"https:\/\/www.danubia.com\/wp-content\/uploads\/2021\/08\/Valos-ideju-fluoreszcencia-alapu-vizsgalat-az-OATP-transzporterek-funkcionalis-tesztelesehez-es-gyogyszer-kolcsonhatasainak-vizsgalatahoz.jpg\" title_text=\"Valos ideju fluoreszcencia alapu vizsgalat az OATP-transzporterek funkcionalis tesztelesehez es gyogyszer-kolcsonhatasainak vizsgalatahoz\" align_tablet=\"center\" align_phone=\"\" align_last_edited=\"on|desktop\" _builder_version=\"4.9.4\" custom_margin=\"||0px|\" custom_padding=\"||15px|\" animation_style=\"fade\" hover_enabled=\"0\" z_index_tablet=\"500\" sticky_enabled=\"0\"][\/et_pb_image][\/et_pb_column][et_pb_column type=\"3_4\" specialty_columns=\"3\" _builder_version=\"3.25\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_row_inner admin_label=\"Sor\" _builder_version=\"3.25\"][et_pb_column_inner saved_specialty_column_type=\"3_4\" _builder_version=\"3.25\" custom_padding=\"|||\" custom_padding__hover=\"|||\"][et_pb_text admin_label=\"N\u00e9v\" _builder_version=\"4.9.4\" text_font=\"Raleway|700||on|||||\" text_text_color=\"#a6192e\" text_font_size=\"26px\" text_line_height=\"1.3em\" header_font=\"Raleway|700||on|||||\" header_text_align=\"center\" header_text_color=\"#ffffff\" header_font_size=\"50px\" header_line_height=\"1.4em\" custom_margin=\"||0px|\" custom_padding=\"||15px|\" hover_enabled=\"0\" text_font_size_tablet=\"22px\" text_font_size_phone=\"20px\" text_font_size_last_edited=\"on|phone\" header_font_size_tablet=\"30px\" header_font_size_phone=\"22px\" header_font_size_last_edited=\"on|desktop\" z_index_tablet=\"500\" sticky_enabled=\"0\"]Val\u00f3s idej\u0171 fluoreszcencia alap\u00fa vizsg\u00e1lat az OATP-transzporterek funkcion\u00e1lis tesztel\u00e9s\u00e9hez \u00e9s gy\u00f3gyszer-k\u00f6lcs\u00f6nhat\u00e1sainak vizsg\u00e1lat\u00e1hoz[\/et_pb_text][et_pb_text admin_label=\"Bejelent\u00e9s \u00fcgysz\u00e1ma, Lajstromsz\u00e1m\" _builder_version=\"4.9.4\" text_font=\"Raleway|700|||||||\" text_text_color=\"#63666a\" text_font_size=\"18px\" custom_margin=\"||0px|\" custom_padding=\"||10px|\" hover_enabled=\"0\" text_font_size_tablet=\"20px\" text_font_size_phone=\"\" text_font_size_last_edited=\"on|desktop\" z_index_tablet=\"500\" sticky_enabled=\"0\"]<\/p>

Reprezentat\u00edv \u00fcgysz\u00e1m: WO\/2021\/123851
Oltalom: Szabadalom
Ipar\u00e1g: gy\u00f3gyszer \u00e9s kozmetikai ipar<\/p>

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R\u00f6vid le\u00edr\u00e1s<\/strong><\/span>
A tal\u00e1lm\u00e1ny az OATP (szerves aniont sz\u00e1ll\u00edt\u00f3 polipeptid) transzportfeh\u00e9rj\u00e9k transzportaktivit\u00e1s\u00e1nak \u00e9rt\u00e9kel\u00e9s\u00e9re, k\u00fcl\u00f6n\u00f6sen egy val\u00f3s idej\u0171, add-and-read fluoreszcencia-alap\u00fa elj\u00e1r\u00e1sra vonatkozik, mely annak meghat\u00e1roz\u00e1s\u00e1ra szolg\u00e1l, miszerint a tesztvegy\u00fclet befoly\u00e1solja-e az OATP szubsztr\u00e1ttranszport-aktivit\u00e1s\u00e1t. Az elj\u00e1r\u00e1s egy nem fluoreszcens kontroll szubsztr\u00e1t alkalmaz\u00e1s\u00e1val val\u00f3sul meg, amely a sejtben fluoreszcens tulajdons\u00e1got mutat fel. A m\u00f3dszer alkalmazhat\u00f3 az OATP expresszi\u00f3j\u00e1nak m\u00e9r\u00e9s\u00e9re \u00e9s a sz\u00e1ll\u00edtott szubsztr\u00e1t valamint az OATP inhibitor k\u00f6z\u00f6tti k\u00fcl\u00f6nbs\u00e9gt\u00e9telre is.<\/p>

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