{"id":8571,"date":"2021-08-03T13:14:09","date_gmt":"2021-08-03T13:14:09","guid":{"rendered":"https:\/\/www.danubia.com\/?post_type=project&p=8571"},"modified":"2022-11-29T22:52:52","modified_gmt":"2022-11-29T22:52:52","slug":"oatps-es-mrp2-transzportaktivitasanak-ertekelesere-szolgalo-fluoreszcencia-alapu-modszer","status":"publish","type":"project","link":"https:\/\/www.danubia.com\/hu\/ipmall\/oatps-es-mrp2-transzportaktivitasanak-ertekelesere-szolgalo-fluoreszcencia-alapu-modszer\/","title":{"rendered":"OATPS \u00e9s MRP2 transzportaktivit\u00e1s\u00e1nak \u00e9rt\u00e9kel\u00e9s\u00e9re szolg\u00e1l\u00f3 fluoreszcencia alap\u00fa m\u00f3dszer"},"content":{"rendered":"

[et_pb_section fb_built=”1″ specialty=”on” _builder_version=”4.16″ inner_max_width=”none” global_colors_info=”{}”][et_pb_column type=”1_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/www.danubia.com\/wp-content\/uploads\/2021\/08\/OATPS-es-MRP2-transzportaktivitasanak-ertekelesere-szolgalo-fluoreszcencia-alapu-modszer.jpg” title_text=”OATPS es MRP2 transzportaktivitasanak ertekelesere szolgalo fluoreszcencia alapu modszer” align_tablet=”center” align_phone=”” align_last_edited=”on|desktop” _builder_version=”4.16″ custom_margin=”||0px|” custom_padding=”||15px|” animation_style=”fade” z_index_tablet=”500″ global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”3_4″ specialty_columns=”3″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_row_inner admin_label=”Sor” _builder_version=”4.16″ global_colors_info=”{}”][et_pb_column_inner saved_specialty_column_type=”3_4″ _builder_version=”4.16″ custom_padding=”|||” global_colors_info=”{}” custom_padding__hover=”|||”][et_pb_text admin_label=”N\u00e9v” _builder_version=”4.16″ text_font=”Raleway|700||on|||||” text_text_color=”#a6192e” text_font_size=”26px” text_line_height=”1.3em” header_font=”Raleway|700||on|||||” header_text_align=”center” header_text_color=”#ffffff” header_font_size=”50px” header_line_height=”1.4em” custom_margin=”||0px|” custom_padding=”||15px|” text_font_size_tablet=”22px” text_font_size_phone=”20px” text_font_size_last_edited=”on|phone” header_font_size_tablet=”30px” header_font_size_phone=”22px” header_font_size_last_edited=”on|desktop” z_index_tablet=”500″ global_colors_info=”{}”]OATPS \u00e9s MRP2 transzportaktivit\u00e1s\u00e1nak \u00e9rt\u00e9kel\u00e9s\u00e9re szolg\u00e1l\u00f3 fluoreszcencia alap\u00fa m\u00f3dszer[\/et_pb_text][et_pb_text admin_label=”Bejelent\u00e9s \u00fcgysz\u00e1ma, Lajstromsz\u00e1m” _builder_version=”4.18.1″ text_font=”Raleway|700|||||||” text_text_color=”#63666a” text_font_size=”18px” custom_margin=”||0px|” custom_padding=”||10px|” hover_enabled=”0″ text_font_size_tablet=”20px” text_font_size_phone=”” text_font_size_last_edited=”on|desktop” z_index_tablet=”500″ global_colors_info=”{}” sticky_enabled=”0″]<\/p>\n

Reprezentat\u00edv \u00fcgysz\u00e1m: WO\/2021\/123847<\/a>
Oltalom: Szabadalom
Ipar\u00e1g: gy\u00f3gyszer \u00e9s kozmetikai ipar<\/p>\n

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R\u00f6vid le\u00edr\u00e1s<\/strong><\/span>
A tal\u00e1lm\u00e1ny az OATP (szerves aniont sz\u00e1ll\u00edt\u00f3 polipeptid) \u00e9s az ABC (ATP k\u00f6t\u0151 kazetta) transzportfeh\u00e9rj\u00e9k transzportaktivit\u00e1s\u00e1nak \u00e9rt\u00e9kel\u00e9s\u00e9re vonatkozik. K\u00f6zelebbr\u0151l, a tal\u00e1lm\u00e1ny olyan elj\u00e1r\u00e1sokra vonatkozik, amelyek egyetlen, fluoreszcencia alap\u00fa vizsg\u00e1latban meghat\u00e1rozz\u00e1k, hogy egy vegy\u00fclet OATP \u00e9s \/ vagy MRP2 (multirezisztens – MDR – asszoci\u00e1lt feh\u00e9rje, ABCC) transzport aktivit\u00e1s\u00e1nak modul\u00e1tora, fluoreszcens vegy\u00fclet felhaszn\u00e1l\u00e1s\u00e1val, amely a mind az OATP, mind az MRP2, \u00e9s az (I) \u00e1ltal\u00e1nos k\u00e9plet\u0171 szulfopir\u00e9nek vagy a (II) \u00e1ltal\u00e1nos k\u00e9plet\u0171 szulforodaminok k\u00f6z\u00fcl van kiv\u00e1lasztva.<\/p>\n

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A tal\u00e1lm\u00e1ny az OATP (szerves aniont sz\u00e1ll\u00edt\u00f3 polipeptid) \u00e9s az ABC (ATP k\u00f6t\u0151 kazetta) transzportfeh\u00e9rj\u00e9k transzportaktivit\u00e1s\u00e1nak \u00e9rt\u00e9kel\u00e9s\u00e9re vonatkozik. K\u00f6zelebbr\u0151l, a tal\u00e1lm\u00e1ny olyan elj\u00e1r\u00e1sokra vonatkozik, amelyek egyetlen, fluoreszcencia alap\u00fa vizsg\u00e1latban meghat\u00e1rozz\u00e1k, hogy egy vegy\u00fclet OATP \u00e9s \/ vagy MRP2 (multirezisztens – MDR – asszoci\u00e1lt feh\u00e9rje, ABCC) transzport aktivit\u00e1s\u00e1nak modul\u00e1tora, fluoreszcens vegy\u00fclet felhaszn\u00e1l\u00e1s\u00e1val, amely a mind az OATP, mind az MRP2, \u00e9s az (I) \u00e1ltal\u00e1nos k\u00e9plet\u0171 szulfopir\u00e9nek vagy a (II) \u00e1ltal\u00e1nos k\u00e9plet\u0171 szulforodaminok k\u00f6z\u00fcl van kiv\u00e1lasztva.<\/p>\n","protected":false},"author":1,"featured_media":8572,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"project_category":[172,186],"project_tag":[],"class_list":["post-8571","project","type-project","status-publish","has-post-thumbnail","hentry","project_category-gyogyszeripar-es-kozmetikai-ipar","project_category-pharmaceutical-and-cosmetics-industry"],"yoast_head":"\nOATPS \u00e9s MRP2 transzportaktivit\u00e1s\u00e1nak \u00e9rt\u00e9kel\u00e9s\u00e9re szolg\u00e1l\u00f3 fluoreszcencia alap\u00fa m\u00f3dszer - Danubia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.danubia.com\/ipmall\/fluorescence-method-for-assessing-transport-activity-of-oatps-and-mrp2\/\" \/>\n<meta property=\"og:locale\" content=\"hu_HU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"OATPS \u00e9s MRP2 transzportaktivit\u00e1s\u00e1nak \u00e9rt\u00e9kel\u00e9s\u00e9re szolg\u00e1l\u00f3 fluoreszcencia alap\u00fa m\u00f3dszer - Danubia\" \/>\n<meta property=\"og:description\" content=\"A tal\u00e1lm\u00e1ny az OATP (szerves aniont sz\u00e1ll\u00edt\u00f3 polipeptid) \u00e9s az ABC (ATP k\u00f6t\u0151 kazetta) transzportfeh\u00e9rj\u00e9k transzportaktivit\u00e1s\u00e1nak \u00e9rt\u00e9kel\u00e9s\u00e9re vonatkozik. 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