Outline
The invention relates to primycin or a primycin component or a combination of primycin components as an active substance, for use in the treatment or prevention of infections caused by methicillin-resistant Staphylococcus aureus (MRSA), methicillin-resistant coagulase-negative Staphylococcus sp. (MRCoNS), vancomycin-intermediate and vancomycin-resistant Staphylococcus aureus (VISA and VRSA), mupirocin-resistant Staphylococcus sp, vancomycin-resistant Enterococci (VRE) or primycin-resistant Streptococcus pneumoniae strains.

The invention also covers antibotic compositions containing these active agents which are preferably applied on the surface of skin or mucous membrane.